The three types of artificial insemination
Skimming the different types of artificial insemination more closely, it’s easy to feel a little bit like you’re drowning in acronyms.
IUI vs ICI and ITI all look and sound similar, but the main difference is actually quite simple: it’s all about where the sperm is placed. And the closer the sperm is placed to where fertilization naturally happens, the shorter the journey it has to make.
1. Intracervical insemination (ICI)
With intracervical insemination (ICI), semen is placed near the cervix, similar to where sperm are deposited during intercourse. Sperm then travel through the cervix and uterus toward the fallopian tubes, where fertilization may occur.
ICI is sometimes referred to as “at-home insemination” because it can be performed outside of a medical office using an at-home insemination kit. It may be an option for some people, including those using donor sperm. Because sperm are placed near the cervix, they have farther to travel and may encounter more potential barriers along the way before reaching the fallopian tubes.
2. Intrauterine insemination (IUI)
Instead of placing semen at the cervix, intrauterine insemination (IUI) uses specially prepared, or “washed,” sperm that is placed directly into the uterus by a healthcare provider. Washing concentrates the healthiest, most motile sperm and removes components of semen that should not be introduced into the uterus.
Placing the prepared sperm directly into the uterus gives it a head start by bypassing the cervix and reducing the distance (and some of the barriers) it must overcome to reach the fallopian tubes, where fertilization may occur.
IUI vs ICI
If you’ve been comparing IUI vs ICI, the biggest difference is that sperm is placed directly into the uterus with IUI, and with ICI, sperm is placed at the cervix.
IUI gets the sperm further along its journey, which is why it’s become a common first-line treatment in many fertility clinics. This said, there’s a third, even more targeted approach to know.
3. Intratubal insemination (ITI)
Intratubal insemination (ITI) builds on the same idea, taking it one step further.
With the FemaSeed procedure, specially prepared sperm is gently placed directly into the fallopian tubes using a specially designed catheter. Since this is where fertilization naturally happens, ITI positions the sperm as close to the egg as possible.
ITI is also a minimally invasive procedure that can be performed in your OB’s office, and is absolutely a treatment option to consider before moving on to more complex procedures like IVF.
Although it’s a newer approach than IUI, it’s one that we’re seeing more and more patients asking about, as awareness grows.
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